publication . Article . 2011

Chemical composition of the essential oil from Kelussia odoratissima Mozaff. and the evaluation of its sedative and anxiolytic effects in mice

mohammad rabbani;
Open Access English
  • Published: 01 Jan 2011 Journal: Clinics (issn: 1807-5932, eissn: 1980-5322, Copyright policy)
  • Publisher: Faculdade de Medicina / USP
Abstract
OBJECTIVE: The present study aimed to evaluate the sedative and anxiolytic effects of the essential oils and hydroalcoholic extract of Kelussia odoratissima Mozaff. (K. odoratissima) in mice by utilizing an elevated plus maze. The chemical composition of its essential oil was also determined. METHODS: The hydroalcoholic extract or essential oil fraction from this plant were administered intraperitoneally to male mice at various doses 30 min before testing. The anxiolytic and sedative effects were determined by an elevated plus maze and locomotor activity tests, respectively. RESULTS: According to the results, none of the administered doses of hydroalcoholic extr...
Subjects
free text keywords: Anti-anxiety, Sedative, Kelussia odoratissima, Elevated plus maze, Locomotor activity, Medicine (General), R5-920, Basic Research, General Medicine, Anxiolytic, medicine.drug_class, medicine, Pharmacology, Chemical composition, Motor activity, Essential oil, law.invention, law, Surgery, medicine.medical_specialty, business.industry, business
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