publication . Article . 1999

Indicators of inflammation and cellular damage in chronic asymptomatic or oligosymptomatic alcoholics: correlation with alteration of bilirubin and hepatic and pancreatic enzymes

Romeu Cardoso Guimarães; Paulo Borini;
Open Access English
  • Published: 01 Apr 1999 Journal: Revista do Hospital das Clínicas (issn: 0041-8781, eissn: 1678-9903, Copyright policy)
  • Publisher: Universidade de São Paulo - FM/USP
Abstract
Biochemical and hematimetric indicators of inflammation and cell damage were correlated with bilirubin and hepatic and pancreatic enzymes in 30 chronic male alcoholics admitted into psychiatric hospital for detoxification and treatment of alcoholism. Aspartate aminotransferase, alanine aminotransferase, gamma-glutamyltransferase, alkaline phosphatase, and total bilirubin were altered, respectively, in 90%, 63%, 87%, 23% and 23% of the cases. None of the indicators of inflammation (lactic dehydrogenase, altered in 16% of the cases; alpha-1 globulin, 24%; alpha-2 globulin, 88%; leucocyte counts, 28%) was correlated with alterations of bilirubin or liver enzymes. L...
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doi: 10.1590/s0041-87811999000200005
Subjects
free text keywords: Alcoholism, Liver, Inflammation, Cell damage, Medicine, R, Medicine (General), R5-920, Alcoolismo, Fígado, Inflamação, Lesão celular, Enzimas, General Medicine, medicine.disease, Alkaline phosphatase, Pancreatitis, Gastroenterology, medicine.medical_specialty, Serum iron, medicine.diagnostic_test, Internal medicine, business.industry, business, Creatine kinase, biology.protein, biology, Bilirubin, chemistry.chemical_compound, chemistry, Hyperamylasemia, Hepatitis
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