publication . Article . 2016

Staphylococcal superantigen-specific IgE antibodies: degree of sensitization and association with severity of asthma

José Elabras Filho; Fernanda Carvalho de Queiroz Mello; Omar Lupi; Blanca Elena Rios Gomes Bica; José Angelo de Souza Papi; Alfeu Tavares França;
Open Access English
  • Published: 01 Oct 2016 Journal: Jornal Brasileiro de Pneumologia (issn: 1806-3756, Copyright policy)
  • Publisher: Sociedade Brasileira de Pneumologia e Tisiologia
ABSTRACT Objective: To determine the presence of staphylococcal superantigen-specific IgE antibodies and degree of IgE-mediated sensitization, as well as whether or not those are associated with the severity of asthma in adult patients. Methods: This was a cross-sectional study involving outpatients with asthma under treatment at a tertiary care university hospital in the city of Rio de Janeiro, Brazil. Consecutive patients were divided into two groups according to the severity of asthma based on the Global Initiative for Asthma criteria: mild asthma (MA), comprising patients with mild intermittent or persistent asthma; and moderate or severe asthma (MSA). We de...
free text keywords: Asma, Imunoglobulina E, Superantígenos, Toxinas bacterianas, Asthma, Immunoglobulin E, Superantigens, Bacterial toxins, Staphylococcus aureus, Diseases of the respiratory system, RC705-779, Original Article, Toxic shock syndrome toxin, Statistical analysis, Tertiary care, Mild asthma, Immunology, Medicine, business.industry, business, medicine.disease, biology.protein, biology, Superantigen, Sensitization, medicine.anatomical_structure
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