publication . Article . 2016

Staphylococcal superantigen-specific IgE antibodies: degree of sensitization and association with severity of asthma

José Elabras Filho; Fernanda Carvalho de Queiroz Mello; Omar Lupi; Blanca Elena Rios Gomes Bica; José Angelo de Souza Papi; Alfeu Tavares França;
Open Access English
  • Published: 01 Oct 2016 Journal: Jornal Brasileiro de Pneumologia (issn: 1806-3756, Copyright policy)
  • Publisher: Sociedade Brasileira de Pneumologia e Tisiologia
Abstract
ABSTRACT Objective: To determine the presence of staphylococcal superantigen-specific IgE antibodies and degree of IgE-mediated sensitization, as well as whether or not those are associated with the severity of asthma in adult patients. Methods: This was a cross-sectional study involving outpatients with asthma under treatment at a tertiary care university hospital in the city of Rio de Janeiro, Brazil. Consecutive patients were divided into two groups according to the severity of asthma based on the Global Initiative for Asthma criteria: mild asthma (MA), comprising patients with mild intermittent or persistent asthma; and moderate or severe asthma (MSA). We de...
Subjects
free text keywords: Asma, Imunoglobulina E, Superantígenos, Toxinas bacterianas, Asthma, Immunoglobulin E, Superantigens, Bacterial toxins, Staphylococcus aureus, Diseases of the respiratory system, RC705-779, Original Article, Toxic shock syndrome toxin, Statistical analysis, Tertiary care, Mild asthma, Immunology, Medicine, business.industry, business, medicine.disease, biology.protein, biology, Superantigen, Sensitization, medicine.anatomical_structure
22 references, page 1 of 2

Dinges, MM, Orwin, PM, Schlievert, PM. Exotoxins of Staphylococcus aureus. Clin Microbiol Rev. 2000; 13 (1): 16-34 [OpenAIRE] [PubMed] [DOI]

Bhatia, A, Zahoor, S. Staphylococcus aureus enterotoxins a review. J Clin Diagn Res. 2007; 1 (3): 188-197

Derycke, L, Pérez-Novo, C, Van Crombruggen, K, Corriveau, M, Bachert, C. Staphylococcus aureus and Chronic Airway Disease. World Allergy Organ J. 2010; 3 (8): 223-228 [OpenAIRE] [PubMed] [DOI]

Heaton, T, Mallo, D, Venaille, T, Holt, P. Staphylococcal enterotoxin induced IL-5 stimulation as a cofactor in the pathogenesis of atopic disease the hygiene hypothesis in reverse?. Allergy. 2003; 58 (3): 252-256 [OpenAIRE] [PubMed] [DOI]

Bachert, C, Zhang, N, Patou, J, Zele, TV, Gevaert, P. Role of staphylococcal superantigens in upper airway disease. Curr Opin Allergy Clin Immunol. 2008; 8 (1): 34-38 [PubMed] [DOI]

Pastacaldi, C, Lewis, P, Howarth, P. Staphylococci and staphylococcal superantigens in asthma and rhinitis a systematic review and meta-analysis. Allergy. 2011; 66 (4): 549-555 [OpenAIRE] [PubMed] [DOI]

Song, WJ, Jo, EJ, Lee, JW, Kang, HR, Cho, SH, Min, KU. Staphylococcal enterotoxin specific IgE and asthma a systematic review and meta-analysis. Asia Pac Allergy. 2013; 3 (2): 120-126 [OpenAIRE] [PubMed] [DOI]

Tomassen, P, Jarvis, D, Newson, R, Van Ree, R, Forsberg, B, Howarth, B. Staphylococcus aureus enterotoxin-specific IgE is associated with asthma in the general population a GA(2)LEN study. Allergy. 2013; 68 (10): 1289-1297 [OpenAIRE] [PubMed] [DOI]

Kowalski, ML, Cieslak, M, Perez-Novo, C, Bachert, C. Association of Staphylococcus aureus sentizitation with severe asthma. J Allergy Clin Immunol.. 2008; 121 (2): S199-S199 [OpenAIRE] [DOI]

Kowalski, ML, Cieslak, M, Pérez-Novo, C, Makowska, JS, Bachert, C. Clinical and immunological determinants of severe/refractory asthma (SRA) association with Staphylococcal superantigen-specific IgE antibodies. Allergy. 2011; 66 (1): 32-38 [OpenAIRE] [PubMed] [DOI]

Bachert, C, Gevaert, P, Howarth, P, Holtappels, G, van Cauwenberge, P, Johansson, SG. IgE to Staphylococcus aureus enterotoxins in serum is related to severity of asthma. J Allergy Clin Immunol. 2003; 111 (5): 1131-1132 [PubMed] [DOI]

Bachert, C, van Steen, K, Zhang, N, Holtappels, G, Cattaert, T, Maus, B. Specific IgE against Staphylococcus aureus enterotoxins An independent risk factor for asthma. J Allergy Clin Immunol. 2012; 130 (2): 376-381 [OpenAIRE] [PubMed] [DOI]

Global Strategy for Asthma Management and Prevention, Global Initiative for Asthma 2004.. 2004

Global Strategy for Asthma Management and Prevention, Global Initiative for Asthma 2006. 2006

Global Strategy for Asthma Management and Prevention, Global Initiative for Asthma 2014.. 2014

22 references, page 1 of 2
Powered by OpenAIRE Research Graph
Any information missing or wrong?Report an Issue