publication . Article . 2016

O estresse oxidativo do cristalino em modelo de rata na menopausa

Acer, S; Pekel, G; Kucukatay, V; Karabulut, A; Yagci, R; Cetin, EN; Akyer, SP; Sahin, B;
Open Access
  • Published: 01 Aug 2016 Journal: Arquivos Brasileiros de Oftalmologia, volume 79, pages 222-225 (issn: 0004-2749, Copyright policy)
  • Publisher: GN1 Genesis Network
  • Country: Turkey
Abstract
ABSTRACT Purpose: To evaluate lenticular oxidative stress in rat menopausal models. Methods: Forty Wistar female albino rats were included in this study. A total of thirty rats underwent oophorectomy to generate a menopausal model. Ten rats that did not undergo oophorectomy formed the control group (Group 1). From the rats that underwent oophorectomy, 10 formed the menopause control group (Group 2), 10 were administered a daily injection of methylprednisolone until the end of the study (Group 3), and the remaining 10 rats were administered intraperitoneal streptozocin to induce diabetes mellitus (Group 4). Total oxidant status (TOS), total antioxidant capacity (...
Subjects
free text keywords: Animals; Antioxidants/analysis/metabolism; Cataract/etiology/metabolism; Diabetes Mellitus, Experimental/metabolism; Female; Glucocorticoids/pharmacology; Humans; Lens, Crystalline/*metabolism; Menopause/*metabolism; Methylprednisolone/pharmacology; Models, Animal; Ovariectomy; Oxidants/metabolism; Oxidative Stress/*physiology; Rats, Wistar; Reference Values; Spectrophotometry, Cataract, Lens, crystalline, Crystalline, Lens, antioxidant, glucocorticoid, oxidizing agent, animal, animal model, experimental diabetes mellitus, female, human, metabolism, ovariectomy, physiology, reference value, spectrophotometry, Wistar rat, Animals, Antioxidants, Diabetes Mellitus, Experimental, Glucocorticoids, Humans, Models, Animal, Oxidants, Rats, Wistar, Menopausa, Catarata, Estress oxidativo, Cristalino, Menopause; Cataract; Oxidative stress; Lens, crystalline, Surgery, medicine.medical_specialty, medicine, Antioxidant capacity, Methylprednisolone, medicine.drug, Diabetes mellitus, medicine.disease, Oophorectomy, medicine.medical_treatment, Streptozocin, Oxidative stress, medicine.disease_cause, Menopause, business.industry, business, Reference values
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publication . Article . 2016

O estresse oxidativo do cristalino em modelo de rata na menopausa

Acer, S; Pekel, G; Kucukatay, V; Karabulut, A; Yagci, R; Cetin, EN; Akyer, SP; Sahin, B;