publication . Other literature type . 2017

A Touchscreen Assay to Probe the Role of the Serotonergic System in Learning and Visual Information Processing

Dorsch, Jeffrey M; Pak, Alexandr; Chubykin, Alexander A;
Open Access
  • Published: 03 Aug 2017
  • Publisher: Purdue University
  • Country: United States
Abstract
The neurotransmitter serotonin is involved in numerous processes in the brain such as behavior, learning, memory, mood, and neurodevelopment. Serotonin signaling is regulated by the serotonin transporter protein (SERT), which maintains normal serotonin levels. Mutations in the SERT gene are known to correlate with cognitive and behavioral deficits seen in psychiatric disorders, such as anxiety disorders, depression, and autism spectrum disorder. Researchers study these deficits using SERT knockout (KO) mice, a model that lacks functional SERT and displays changes in anxiety, learning, and motivation. We are interested in how the absence of SERT affects visual pr...
Subjects
Medical Subject Headings: education
free text keywords: Serotonin, operant conditioning, sensory processing, global motion perception, knockout mice, Behavioral Neurobiology, Cognitive Neuroscience
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Other literature type . 2017
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