publication . Other literature type . Article . 2015 . Embargo end date: 01 Jun 2015

Correlation between alveolar ventilation and electrical properties of lung parenchyma.

Christian J Roth; Andreas Ehrl; Tobias Becher; Inéz Frerichs; Johannes C Schittny; Norbert Weiler; Wolfgang A Wall;
Restricted English
  • Published: 26 May 2015
  • Publisher: Institute of Physics Publishing IOP
  • Country: Germany
Abstract
One key problem in modern medical imaging is linking measured data and actual physiological quantities. In this article we derive such a link between the electrical bioimpedance of lung parenchyma, which can be measured by electrical impedance tomography (EIT), and the magnitude of regional ventilation, a key to understanding lung mechanics and developing novel protective ventilation strategies. Two rat-derived three-dimensional alveolar microstructures obtained from synchrotron-based x-ray tomography are each exposed to a constant potential difference for different states of ventilation in a finite element simulation. While the alveolar wall volume remains cons...
Subjects
Medical Subject Headings: respiratory system
free text keywords: Ingenieurwissenschaften, lung impedance, tissue properties, alveolar geometry, ventilation monitoring, lung volume, 610 Medicine & health, ddc:620, Biophysics, Physiology (medical), Physiology, Biomedical Engineering, Pathology, medicine.medical_specialty, medicine, Tomography, Alveolar Wall, Ventilation (architecture), law.invention, law, Lung volumes, Electronic engineering, Breathing, Electrical impedance tomography, Parenchyma, Lung, medicine.anatomical_structure, business.industry, business
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publication . Other literature type . Article . 2015 . Embargo end date: 01 Jun 2015

Correlation between alveolar ventilation and electrical properties of lung parenchyma.

Christian J Roth; Andreas Ehrl; Tobias Becher; Inéz Frerichs; Johannes C Schittny; Norbert Weiler; Wolfgang A Wall;