Simultaneous imaging of multiple neurotransmitters and neuroactive substances in the brain by desorption electrospray ionization mass spectrometry

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Shariatgorji, Mohammadreza; Strittmatter, Nicole; Nilsson, Anna; Kallbäck, Patrik; Alvarsson, Alexandra; Zhang, Xiaoqun; Vallianatou, Theodosia; Svenningsson, Per; Goodwin, Richard J. A.; Andrén, Per E.;
  • Publisher: AstraZeneca, Drug Safety & Metab, Cambridge CB4 0WG, England.
  • Related identifiers: doi: 10.1016/j.neuroimage.2016.05.004
  • Subject: Neurotransmitter | Dopamine | Imaging | Mass spectrometry | Parkinson's disease | Serotonin | Neurology | Neurologi | Radiology, Nuclear Medicine and Medical Imaging | Radiologi och bildbehandling

With neurological processes involving multiple neurotransmitters and neuromodulators, it is important to have the ability to directly map and quantify multiple signaling molecules simultaneously in a single analysis. By utilizing a molecular-specific approach, namely de... View more
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