publication . Book . Doctoral thesis . 2009

Acoustic manipulation of particles and fluids in microfluidic systems

Erik Staijen;
Open Access
  • Published: 01 Jan 2009
  • Country: Sweden
Abstract
The downscaling and integration of biomedical analyses onto a single chip offers several advantages in speed, cost, parallelism and de-centralization. Acoustic radiation forces are attractive to use in these applications since they are strong, long-range and gentle. Lab-on-a-chip operations such as cell trapping, particle fluorescence activated cell sorting, fluid mixing and particle sorting performed by acoustic radiation forces are exploited in this thesis. Two different platforms are designed, manufactured and evaluated.
Subjects
free text keywords: Acoustics, Akustik
Related Organizations
116 references, page 1 of 8

D. J. Beebe, G. A. Mensing and G. M. Walker, Annu Rev Biomed Eng, 2002, 4, 261-286.

H. Andersson and A. van den Berg, Sensor Actuat B-Chem, 2003, 92, 315-325.

S. M. Coward, C. Selden, A. Mantalaris and H. J. F. Hodgson, Artif Organs, 2005, 29, 152-158.

F. A. Gomez, Biological applications of microfluidics, 1 edn., John Wiley & Sons, Inc., Hoboken, 2008.

Brismar, Electrophoresis, 2007, 28, 4705-4712.

A. Manz, N. Graber and H. M. Widmer, Sensor Actuat B-Chem, 1990, 1, 244-248.

S. Haeberle and R. Zengerle, Lab Chip, 2007, 7, 1094-1110.

Fuller, R. G. Larson, D. T. Burke and M. A. Burns, Lab Chip, 2005, 5, 1024-1032.

German cancer research center, 20090314, http://www.dkfz.de/gpcf/24.html F. K. Balagadde, L. C. You, C. L. Hansen, F. H. Arnold and S. R.

Quake, Science, 2005, 309, 137-140.

D. Jens, H. Stefan, L. Sascha, P. Sarah, S. Felix von and Z. Roland, J Micromech Microeng, 2007, S103.

F. Petersson, L. Aberg, A. M. Sward-Nilsson and T. Laurell, Anal Chem, 2007, 79, 5117-5123.

C. H. J. Schmitz, A. C. Rowat, S. Koster and D. A. Weitz, Lab Chip, 2009, 9, 44-49.

D. Bazou, W. T. Coakley, K. M. Meek, M. Yang and D. T. Pham, Colloid Surface A, 2004, 243, 97-104.

D. Bazou, L. A. Kuznetsova and W. T. Coakley, Ultrasound Med Biol, 2005, 31, 423-430.

116 references, page 1 of 8
Abstract
The downscaling and integration of biomedical analyses onto a single chip offers several advantages in speed, cost, parallelism and de-centralization. Acoustic radiation forces are attractive to use in these applications since they are strong, long-range and gentle. Lab-on-a-chip operations such as cell trapping, particle fluorescence activated cell sorting, fluid mixing and particle sorting performed by acoustic radiation forces are exploited in this thesis. Two different platforms are designed, manufactured and evaluated.
Subjects
free text keywords: Acoustics, Akustik
Related Organizations
116 references, page 1 of 8

D. J. Beebe, G. A. Mensing and G. M. Walker, Annu Rev Biomed Eng, 2002, 4, 261-286.

H. Andersson and A. van den Berg, Sensor Actuat B-Chem, 2003, 92, 315-325.

S. M. Coward, C. Selden, A. Mantalaris and H. J. F. Hodgson, Artif Organs, 2005, 29, 152-158.

F. A. Gomez, Biological applications of microfluidics, 1 edn., John Wiley & Sons, Inc., Hoboken, 2008.

Brismar, Electrophoresis, 2007, 28, 4705-4712.

A. Manz, N. Graber and H. M. Widmer, Sensor Actuat B-Chem, 1990, 1, 244-248.

S. Haeberle and R. Zengerle, Lab Chip, 2007, 7, 1094-1110.

Fuller, R. G. Larson, D. T. Burke and M. A. Burns, Lab Chip, 2005, 5, 1024-1032.

German cancer research center, 20090314, http://www.dkfz.de/gpcf/24.html F. K. Balagadde, L. C. You, C. L. Hansen, F. H. Arnold and S. R.

Quake, Science, 2005, 309, 137-140.

D. Jens, H. Stefan, L. Sascha, P. Sarah, S. Felix von and Z. Roland, J Micromech Microeng, 2007, S103.

F. Petersson, L. Aberg, A. M. Sward-Nilsson and T. Laurell, Anal Chem, 2007, 79, 5117-5123.

C. H. J. Schmitz, A. C. Rowat, S. Koster and D. A. Weitz, Lab Chip, 2009, 9, 44-49.

D. Bazou, W. T. Coakley, K. M. Meek, M. Yang and D. T. Pham, Colloid Surface A, 2004, 243, 97-104.

D. Bazou, L. A. Kuznetsova and W. T. Coakley, Ultrasound Med Biol, 2005, 31, 423-430.

116 references, page 1 of 8
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