The role of autonomic function in exercise-induced endogenous analgesia : a case-control study in myalgic encephalomyelitis/chronic fatigue syndrome and healthy people

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Van Oosterwijck, Jessica; Marusic, Uros; De Wandele, Inge; Paul, Lorna; Meeus, Mira; Moorkens, Greta; Lambrecht, Luc; Danneels, Lieven; Nijs, Jo;
  • Journal: Pain physician (issn: 1533-3159)
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  • Subject: AEROBIC EXERCISE | pain | autonomic nervous system | PERIPHERAL MUSCLE | RELIABILITY | PHYSICAL-ACTIVITY INTENSITY | stress-induced analgesia | exercise-induced analgesia | aerobic power index | FIBROMYALGIA | heart rate variability | NERVOUS-SYSTEM | exercise-induced hypoalgesia | PAIN THRESHOLDS | Medicine and Health Sciences | BLOOD-PRESSURE | MECHANISMS | OXIDATIVE STRESS | Human medicine

Abstract: Background: Patients with myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) are unable to activate brain-orchestrated endogenous analgesia (or descending inhibition) in response to exercise. This physiological impairment is currently regarded as on... View more
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