publication . Article . 2012

Consortium biology in immunology: The perspective from the Immunological Genome Project

Benoist, C; Lanier, L; Merad, M; Mathis, D; Ericson, J; Painter, M; Davis, S; Laplace, C; Hyatt, G; Paik, H; ...
Open Access English
  • Published: 01 Oct 2012
  • Publisher: eScholarship, University of California
  • Country: United States
Although the field has a long collaborative tradition, immunology has made less use than genetics of 'consortium biology', wherein groups of investigators together tackle large integrated questions or problems. However, immunology is naturally suited to large-scale integrative and systems-level approaches, owing to the multicellular and adaptive nature of the cells it encompasses. Here, we discuss the value and drawbacks of this organization of research, in the context of the long-running 'big science' debate, and consider the opportunities that may exist for the immunology community. We position this analysis in light of our own experience, both positive and ne...
free text keywords: Immunological Genome Project, Animals, Humans, Biology, Genomics, Immunogenetics, Allergy and Immunology, Science, Research
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