publication . Doctoral thesis . 2007

Computational tools for high-throughput discovery in biology

Jones, Neil Christopher;
Open Access
  • Published: 01 Jan 2007
  • Publisher: eScholarship, University of California
  • Country: United States
High throughput data acquisition technology has inarguably transformed the landscape of the life sciences, in part by making possible---and necessary---the computational disciplines of bioinformatics and biomedical informatics. These fields focus primarily on developing tools for analyzing data and generating hypotheses about objects in nature, and it is in this context that we address three pressing problems in the fields of the computational life sciences which each require computing capacity beyond that obtainable in a single computer. We develop an alignment- free method for identifying conserved motif instances from orthologous promoters in mammalian genome...
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