publication . Doctoral thesis . 2017

Characterization of the Spinal Disc-Vertebra Interface and its Relation to Injury and Back Pain

Berg-Johansen, Britta;
Open Access English
  • Published: 01 Jan 2017
  • Publisher: eScholarship, University of California
  • Country: Mexico
Back pain is the most common musculoskeletal condition, affecting 80% of Americans during their lifetimes. Irregularities of the spinal disc-vertebra interface are associated with back pain and over 60% of disc herniation injuries. Despite the vulnerability of this interface, its structure and function are not well characterized. This dissertation explores the structural and biomechanical features of the disc-vertebra interface, with the goal of motivating improved diagnostics and treatments for back pain patients. Towards this goal, this dissertation is broken into four studies. In the first, we show that bending strength and flexibility of the disc-vertebra in...
free text keywords: Biomechanics, Biomedical engineering, cartilage endplate avulsion, disc herniation, disc-vertebra interface, lumbar spine, structure-function analysis
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