publication . Article . 2016

Generalized morphea as the first sign of breast carcinoma: a case report

Desmond, Bryce L; Blattner, Collin M; Young III, John;
Open Access English
  • Published: 01 Jan 2016
  • Publisher: eScholarship, University of California
  • Country: United States
Generalized morphea is a rare idiopathic form of scleroderma that literally means “hard skin.” Morphea is usually considered an isolated event that is not associated with malignancy. However, case reports of lung, hematologic, and breast cancer occurring simultaneously with large plaque morphea have caused dermatologists to question whether a work-up for malignancy is appropriate. We highlight a case of generalized morphea that preceded invasive ductal carcinoma of the breast and provide a discussion about the possible paraneoplastic origin of generalized morphea and systemic sclerosis (SSc).
Medical Subject Headings: skin and connective tissue diseasesintegumentary system
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