Fall in C-peptide during first 2 years from diagnosis: Evidence of at least two distinct phases from composite type 1 diabetes trialnet data

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Gitelman, Stephen; Greenbaum, CJ; Beam, CA; Boulware, D; Gitelman, SE; Gottlieb, PA; Herold, KC; Lachin, JM; McGee, P; Palmer, JP; Pescovitz, MD;
  • Publisher: eScholarship, University of California

Interpretation of clinical trials to alter the decline in β-cell function after diagnosis of type 1 diabetes depends on a robust understanding of the natural history of disease. Combining data from the Type 1 Diabetes TrialNet studies, we describe the natu
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