The mechanism of recognition and processing of DNA damage and modifications by RNA polymerase II

Doctoral thesis English OPEN
Shin, JI;
  • Publisher: eScholarship, University of California
  • Subject: Biology | Biochemistry | DNA damage | DNA modifications | RNA polymerase II | transcription

RNA polymerase II (pol II) recognizes many obstacles during transcription elongation, including DNA damage lesions and modifications, via specific interactions and leads to distinct transcriptional outcomes. We investigate three specific types of modifications/lesions i... View more
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