Chemoselective synthesis of functional homocysteine residues in polypeptides and peptides

Article English OPEN
Gharakhanian, EG ; Deming, TJ (2016)
  • Publisher: eScholarship, University of California

A methodology was developed for efficient, chemoselective transformation of methionine residues into stable, functional homocysteine derivatives. Methionine residues can undergo highly chemoselective alkylation reactions at low pH to yield stable sulfonium ions, which c... View more
Share - Bookmark