publication . Article . 2000

BioSig: A bioinformatic system for studying the mechanism of intra-cell signaling

Parvin, B.; Cong, G.; Fontenay, G.; Taylor, J.; Henshall, R.; Barcellos-Hoff, M.H.;
Open Access English
  • Published: 15 Dec 2000
  • Publisher: eScholarship, University of California
  • Country: United States
Mapping inter-cell signaling pathways requires an integrated view of experimental and informatic protocols. BioSig provides the foundation of cataloging inter-cell responses as a function of particular conditioning, treatment, staining, etc. for either in vivo or in vitro experiments. This paper outlines the system architecture, a functional data model for representing experimental protocols, algorithms for image analysis, and the requried statistical analysis. The architecture provides remote shared operation of an inverted optical microscope, and couples instrument operation with images acquisition and annotation. The information is stored in an object-oriente...
free text keywords: Life Sciences
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