A Simplified Model of Glycoprotein Production within Cell Culture

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Lambert, A. B.; Smith, F. T.; Velayudhan, A.;
  • Publisher: Cambridge University Press (CUP)
  • Subject: Mathematical Model, Glycosylation, Post-translational modification, Bioreactor

Complex biological products, such as those used to treat various forms of cancer, are typically produced by mammalian cells in bioreactors. The most important class of such biological medicines is proteins. These typically bind to sugars (glycans) in a process known as ... View more
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