publication . Article . Other literature type . 2017

Cost-effectiveness of screening for HIV in primary care : a health economics modelling analysis

Baggaley, Rebecca F.; Irvine, Michael A.; Leber, Werner; Cambiano, Valentina; Figueroa, Jose; McMullen, Heather; Anderson, Jane; Santos, Andreia C.; Terris-Prestholt, Fern; Miners, Alec; ...
Open Access English
  • Published: 01 Oct 2017
  • Country: United Kingdom
Abstract
Summary Background Early HIV diagnosis reduces morbidity, mortality, the probability of onward transmission, and their associated costs, but might increase cost because of earlier initiation of antiretroviral treatment (ART). We investigated this trade-off by estimating the cost-effectiveness of HIV screening in primary care. Methods We modelled the effect of the four-times higher diagnosis rate observed in the intervention arm of the RHIVA2 randomised controlled trial done in Hackney, London (UK), a borough with high HIV prevalence (≥0·2% adult prevalence). We constructed a dynamic, compartmental model representing incidence of infection and the effect of scree...
Subjects
Medical Subject Headings: health care economics and organizations
free text keywords: Gynecology, medicine.medical_specialty, medicine, Randomized controlled trial, law.invention, law, Transmission (mechanics), Epidemiology, Gerontology, Public health, Family medicine, Primary care, Credible interval, business.industry, business, Health economics, Cost database, Articles, Science & Technology, Life Sciences & Biomedicine, Immunology, Infectious Diseases, ANTIRETROVIRAL THERAPY, PREEXPOSURE PROPHYLAXIS, PREVENTION, INITIATION, INFECTION, TRIAL, MEN, SEX, RA
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