Amines, Astrocytes and Arousal

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Bazargani, N. ; Attwell, D. (2017)
  • Publisher: CELL PRESS
  • Subject: astrocyte; monoamine; noradrenaline; glutamate; mitochondrion; gliotransmission; calcium; TRP channel; Water witch; Drosophila
    mesheuropmc: fungi

Amine neurotransmitters, such as noradrenaline, mediate arousal, attention, and reward in the CNS. New data suggest that, from flies to mammals, a major mechanism for amine transmitter action is to raise astrocyte [Ca2+]i and release gliotransmitters that modulate neuronal activity and behavior.
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