Elevated Striatal Dopamine Function in Immigrants and Their Children:A Risk Mechanism for Psychosis

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Egerton, Alice ; Howes, Oliver D ; Houle, Sylvain ; McKenzie, Kwame ; Valmaggia, Lucia R ; Bagby, Michael R ; Tseng, Huai-Hsuan ; Bloomfield, Michael A P ; Kenk, Miran ; Bhattacharyya, Sagnik ; Suridjan, Ivonne ; Chaddock, Chistopher A ; Winton-Brown, Toby T ; Allen, Paul ; Rusjan, Pablo ; Remington, Gary ; Meyer-Lindenberg, Andreas ; McGuire, Philip K ; Mizrahi, Romina (2017)
  • Publisher: OXFORD UNIV PRESS
  • Journal: volume 43, issue 2, pages 293-301 (issn: 0586-7614, eissn: 1745-1701)
  • Related identifiers: pmc: PMC5605255, doi: 10.1093/schbul/sbw181
  • Subject: stress | schizophrenia, stress, positron emission tomography | schizophrenia | positron emission tomography | Invited Themed Article

Abstract Migration is a major risk factor for schizophrenia but the neurochemical processes involved are unknown. One candidate mechanism is through elevations in striatal dopamine synthesis and release. The objective of this research was to determine whether striatal d... View more
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