publication . Thesis . 1999

Scale-up of precipitation processes

Zauner, R.;
Open Access English
  • Published: 01 Jan 1999
  • Publisher: University of London
  • Country: United Kingdom
Abstract
This thesis concerns the scale-up of precipitation processes aimed at predicting product particle characteristics. Although precipitation is widely used in the chemical and pharmaceutical industry, successful scale-up is difficult due to the absence of a validated methodology. It is found that none of the conventional scale-up criteria reported in the literature (equal power input per unit mass, equal tip speed, equal stirring rate) is capable of predicting the experimentally observed effects of the mixing conditions on kinetic rates and particle characteristics. As a result of high gradients in the supersaturation field during precipitation, particularly in the...
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Thesis . 1999
Provider: UCL Discovery
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