publication . Thesis . 2016

An investigation into UV-curable gel formulations for topical nail medicines

Kerai, L. V.;
Open Access English
  • Published: 28 Dec 2016
  • Publisher: UCL (University College London)
  • Country: United Kingdom
Abstract
UV gels are nail cosmetics which are applied on the nail plate surface and polymerised by placing the nail under a UVA nail lamp. The polymeric film formed can reside on the nail plate for up to 3 weeks without developing any visible defects. Using such a formulation as a drug carrier for the treatment of nail diseases, e.g. fungal infections, could address current issues with topical formulations, such as the failure to maintain a drug depot at the desired site and the need for frequent applications. The aim of this thesis was thus to formulate pharmaceutical UV-curable gels, using antifungals as test drugs, and characterise the resulting film’s properties, suc...
Subjects
Medical Subject Headings: integumentary systemskin and connective tissue diseases
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Thesis . 2016
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