publication . Article . 2001

Impulsive Traits and 5-HT2A Receptor Promoter Polymorphism in Alcohol Dependents: Possible Association but No Influence of Personality Disorders

Preuss, Ulrich W.; Koller, G.; Bondy, Brigitta; Bahlmann, Miriam; Soyka, Michael;
Open Access
  • Published: 01 Jan 2001 Journal: Neuropsychobiology, volume 43, pages 186-191 (issn: 0302-282X, eissn: 1423-0224, Copyright policy)
  • Publisher: S. Karger AG
  • Country: Germany
Abstract
Objective: Impulsive behavior in alcoholics puts them at serious risk of severer course of disease and has been related to the serotonergic neurotransmission dysfunction. The aim of this study is to investigate the association between impulsive aggression in alcohol dependents with regard to the G-1438A polymorphism in the promoter region of the 5-HT2A receptor gene. Furthermore, we investigated the statistical interaction between 5-HT2A alleles, antisocial personality disorder (APD) and impulsive aggression in alcohol dependents. Alcohol dependents were investigated because these personality disorders and impulsive behavior are very frequent in alcohol dependen...
Subjects
free text keywords: Medizin, Borderline personality disorder, medicine.disease, medicine, Alcohol dependence, Barratt Impulsiveness Scale, Allele, Personality disorders, Polymorphism (computer science), Psychiatry, medicine.medical_specialty, Psychology, Impulsivity, medicine.symptom, Antisocial personality disorder, ddc:610
Related Organizations
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publication . Article . 2001

Impulsive Traits and 5-HT2A Receptor Promoter Polymorphism in Alcohol Dependents: Possible Association but No Influence of Personality Disorders

Preuss, Ulrich W.; Koller, G.; Bondy, Brigitta; Bahlmann, Miriam; Soyka, Michael;