publication . Conference object . Article . 2002

Evaluation of toxic and protective effects of an essential oil of salvia officinalis L on liver cells

Lima C.,; Carvalho F.,; Fernandes E.,; Bastos M.L.,; Santos-Gomes P.,; Manuel Fernandes-Ferreira; Pereira-Wilson C.;
Open Access English
  • Published: 01 Sep 2002
  • Country: Brazil
The widespread use of sage (Salvia officinalis L.) in herbal teas and as a food condiment requires that studies of their biological effects are conducted in order to prevent ill effects on human health. It is known that the essential oil (EO) of this plant is neurotoxic, but in higher concentrations than those used in the applications referred above. In this study we have isolated and characterized the EO of S. officinalis and studied its toxic/protective effects in rat hepatocytes isolated by collagenase perfusion. The aims were to determine: 1. whether the use of the S. officinalis EO for human consumption has any adverse effects to the liver in the concentrat...
free text keywords: Salvia officinalis, Hepatotoxicity, Essential oil, Protective effects
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