publication . Article . Other literature type . 2018

Gamma irradiation effects on ochratoxin A: Degradation, cytotoxicity and application in food

Thalita Calado; María Luisa Fernández-Cruz; Sandra Cabo Verde; Armando Venâncio; Luís Abrunhosa;
Open Access English
  • Published: 01 Feb 2018
  • Publisher: Elsevier
  • Country: Brazil
Abstract
Ochratoxin A (OTA) is one of the main mycotoxins that can be found in food. The use of gamma radiation is a technique for preserving food that may exert some effects on mycotoxins. OTA was irradiated in its dry form, in aqueous and in methanolic solutions, and in wheat flour, grape juice and wine. Additionally, the toxicity of OTA irradiated in water was tested. In aqueous solutions, more than 90% of the OTA was degraded by -radiation doses 2.5 kGy, and a 2-fold reduction in OTA cytotoxicity was observed. In food matrices, the elimination of OTA by -radiation was found more difficult, as radiation doses of 30 kGy eliminate at most 24% of the OTA. Higher moisture...
Subjects
free text keywords: Ochratoxin A, Cytotoxicity, Gamma irradiation, Grape juice, Wheat flour, Wine, Science & Technology, Mycotoxin, chemistry.chemical_compound, chemistry, Toxicity, Ochratoxin A degradation, Irradiation, Aqueous solution, Food science, Chromatography
Funded by
FCT| UID/BIO/04469/2013
Project
UID/BIO/04469/2013
Centre of Biological Engineering - University of Minho
  • Funder: Fundação para a Ciência e a Tecnologia, I.P. (FCT)
  • Project Code: 147337
  • Funding stream: 5876
,
FCT| UID/Multi/04349/2013
Project
UID/Multi/04349/2013
Centre for Nuclear Sciences and Technologies
  • Funder: Fundação para a Ciência e a Tecnologia, I.P. (FCT)
  • Project Code: 147266
  • Funding stream: 5876
,
FCT| RECI/BBB-EBI/0179/2012
Project
RECI/BBB-EBI/0179/2012
Consolidating Research Expertise and Resources on Cellular and Molecular Biotechnology at CEB/IBB
  • Funder: Fundação para a Ciência e a Tecnologia, I.P. (FCT)
  • Project Code: 126270
  • Funding stream: COMPETE
,
FCT| RECI/AAG-TEC/0400/2012
Project
RECI/AAG-TEC/0400/2012
Application of Ionizing Radiation for a Sustainable Environment
  • Funder: Fundação para a Ciência e a Tecnologia, I.P. (FCT)
  • Project Code: 129707
  • Funding stream: 3599-PPCDT
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publication . Article . Other literature type . 2018

Gamma irradiation effects on ochratoxin A: Degradation, cytotoxicity and application in food

Thalita Calado; María Luisa Fernández-Cruz; Sandra Cabo Verde; Armando Venâncio; Luís Abrunhosa;