publication . Article . Other literature type . 2011

High-throughput evaluation of interactions between biomaterials, proteins and cells using patterned superhydrophobic substrates

João Mano; Catarina Custodio; Catarina Custodio; Isabel Neto; Ana Neto;
Open Access
  • Published: 04 Mar 2011 Journal: Soft Matter, volume 7, page 4,147 (issn: 1744-683X, eissn: 1744-6848, Copyright policy)
  • Publisher: Royal Society of Chemistry (RSC)
  • Country: Portugal
Abstract
We propose a new low cost platform for high-throughput analysis that permits screening the biological performance of independent combinations of biomaterials, cells and culture media. Patterned superhydrophobic flat substrates with controlled wettable spots are used to produce microarray chips for accelerated multiplexing evaluation.
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Subjects
free text keywords: General Chemistry, Condensed Matter Physics, Superhydrophobic surfaces, Cell-materials interactions, Science & Technology, Multiplexing, High-throughput screening, Materials science, Protein adsorption, Throughput, Tissue engineering, Nanotechnology
Related Organizations
Funded by
FCT| PTDC/FIS/68517/2006
Project
PTDC/FIS/68517/2006
ProteoLight - Evaluation and development of fluorescent probe techniques for the study of protein conformation on polymer surfaces.
  • Funder: Fundação para a Ciência e a Tecnologia, I.P. (FCT)
  • Project Code: 68517
  • Funding stream: 5876-PPCDTI
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