publication . Doctoral thesis . 2010

Modulation of limbic noradrenergic circuits by cannabinoids

Carvalho, Ana Raquel Franky Gomes;
Open Access Portuguese
  • Published: 07 Dec 2010
  • Country: Brazil
Tese de doutoramento Medicina The endocannabinoid system has been implicated in the regulation of several physiological functions. The widespread distribution of the endocannabinoid system in the central nervous system (CNS) accounts for many effects attributed to cannabinoids. Importantly, cannabinoids have been shown to modulate mood, cognition and memory. There is growing evidence suggesting that cannabinoids can interact with the noradrenergic system. Noradrenergic transmission in the CNS has also been implicated in the regulation of mood, cognition and memory. In the present work, the hypothesis that cannabinoids can impact noradrenergic transmission in the...
free text keywords: 612.821
Related Organizations
79 references, page 1 of 6

Arguello, P. A. & Jentsch, J.D. (2004) Cannabinoid CB1 receptor-mediated impairment of visuospatial attention in the rat. Psychopharmacology (Berl), 177, 141-150. [OpenAIRE]

Aston-Jones, G. (2002) Norepinephrine. In Davis, K. L., Charney, D., Coyle, J. T. & Nemeroff, C. , Neuropsychopharmacology: The Fifth Generation of Progress. Lippincott, Williams & Wilkins, Philadelphia, USA, pp. 47-57.

Aston-Jones, G., Delfs, J.M., Druhan, J. & Zhu, Y. (1999a) The bed nucleus of the stria terminalis. A target site for noradrenergic actions in opiate withdrawal. Ann. N. Y. Acad. Sci., 877, 486-498.

Aston-Jones, G., Rajkowski, J. & Cohen, J. (1999b) Role of locus coeruleus in attention and behavioral flexibility. Biol. Psychiatry, 46, 1309-1320. [OpenAIRE]

Bardo, M. T. & Bevins, R.A. (2000) Conditioned place preference: What does it add to our preclinical understanding of drug reward? Psychopharmacology (Berl), 153, 31-43. [OpenAIRE]

Barraco, R., el-Ridi, M., Ergene, E., Parizon, M. & Bradley, D. (1992) An atlas of the rat subpostremal nucleus tractus solitarius. Brain Res. Bull., 29, 703-765.

Bisogno, T., Howell, F., Williams, G., Minassi, A., Cascio, M.G., Ligresti, A., Matias, I., SchianoMoriello, A., Paul, P., Williams, E.J., Gangadharan, U., Hobbs, C., Di Marzo, V. & Doherty, P. (2003) Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. J. Cell Biol., 163, 463-468. [OpenAIRE]

Breivogel, C. S., Sim, L.J. & Childers, S.R. (1997) Regional differences in cannabinoid receptor/G-protein coupling in rat brain. J. Pharmacol. Exp. Ther., 282, 1632-1642. [OpenAIRE]

Buczynski, M. W. & Parsons, L.H. (2010) Quantification of brain endocannabinoid levels: Methods, interpretations and pitfalls. Br. J. Pharmacol., 160, 423-442. [OpenAIRE]

Carlezon, W. A.,Jr & Thomas, M.J. (2009) Biological substrates of reward and aversion: A nucleus accumbens activity hypothesis. Neuropharmacology, 56 Suppl 1, 122-132.

Carlezon, W. A.,Jr (2003) Place conditioning to study drug reward and aversion. Methods Mol. Med., 84, 243-249.

Carr, G. D. & White, N.M. (1986) Anatomical disassociation of amphetamine's rewarding and aversive effects: An intracranial microinjection study. Psychopharmacology (Berl), 89, 340-346.

Carr, G. D. & White, N.M. (1983) Conditioned place preference from intra-accumbens but not intra-caudate amphetamine injections. Life Sci., 33, 2551-2557.

Cecchi, M., Capriles, N., Watson, S.J. & Akil, H. (2007) Beta1 adrenergic receptors in the bed nucleus of stria terminalis mediate differential responses to opiate withdrawal. Neuropsychopharmacology, 32, 589-599.

Cecchi, M., Khoshbouei, H., Javors, M. & Morilak, D.A. (2002) Modulatory effects of norepinephrine in the lateral bed nucleus of the stria terminalis on behavioral and neuroendocrine responses to acute stress. Neuroscience, 112, 13-21. [OpenAIRE]

79 references, page 1 of 6
Powered by OpenAIRE Open Research Graph
Any information missing or wrong?Report an Issue