Predictions of RNA-binding ability and aggregation propensity of proteins

Doctoral thesis English OPEN
Agostini, Federico, 1985-;
(2014)
  • Publisher: Universitat Pompeu Fabra
  • Subject: Intrinsically disordered region (IDR) | Long non-coding RNA (lncRNA) | Low-complexity sequence (LCS) | Protein aggregate | Ribonucleoprotein complex (RNP complex) | RNA granule | RNA recognition element (RRE) | RNA-binding protein (RBP) | Stress granules | Región intrínsecamente desordenada | ARN largo no codificante | Secuencia de baja complejidad | Agregado proteico | Complejo de ribonucleoproteína | Gránulo de ARN | Elemento de reconocimiento de ARN | Proteína de unión al ARN | Gránulos de estrés | 577

RNA-binding proteins (RBPs) control the fate of a multitude of coding and non-coding transcripts. Formation of ribonucleoprotein (RNP) complexes fine-tunes regulation of post-transcriptional events and influences gene expression. Recently, it has been observed that non-... View more
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