Reprogramming of B cells into macrophages: mechanistic insights

Doctoral thesis English OPEN
Di Tullio, Alessandro, 1982-;
(2012)
  • Publisher: Universitat Pompeu Fabra
  • Subject: Reprogramación de linaje | Retro-diferenciación | Dependencia del ciclo celular | C/EBPα | Decisión de destino celular | Diferenciación hematopoyética | Lineage reprogramming | Retrodifferentiation | Cell cycle-dependency | Cell fate decision | Hematopoietic differentiation | 576

Our earlier work has shown that pre-B cells can be converted into macrophages by the transcription factor C/EBPα at very high frequencies and also that a clonal pre-B cell line with an inducible form of C/EBPα can be converted into macrophage-like cells. Using these sys... View more
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