publication . Other literature type . Article . 2006

Local Structure of β-Hairpin Isotopomers by FTIR, 2D IR, and Ab Initio Theory

Jianping Wang; Jianxin Chen; Robin M. Hochstrasser;
Open Access English
  • Published: 13 Apr 2006
Abstract
The 12-residue tryptophan zipper β-hairpin (SWTWENGKWTWK) and two 13C-isotopomers were examined in the amide-I region using FTIR and femtosecond two-dimensional infrared (2D IR) spectroscopies. Spectroscopic features of the labeled transitions with 13C-substituted amide unit present in the terminal or turn region of the hairpin, including their frequency shifts and distributions, line broadenings, orientations and anharmonicities of diagonal peaks, allow the peptide local structure and local environment to be examined. The results suggest a larger structure fluctuation in the terminal region than in the turn region as a result of the side chain effect and solven...
Subjects
free text keywords: Article, Physical and Theoretical Chemistry, Materials Chemistry, Surfaces, Coatings and Films, Photochemistry, Computational chemistry, Crystallography, Femtosecond, Chemistry, Isotopomers, Delocalized electron, Protein structure, Side chain, Degenerate energy levels, Infrared, Amide, chemistry.chemical_compound
Powered by OpenAIRE Open Research Graph
Any information missing or wrong?Report an Issue
publication . Other literature type . Article . 2006

Local Structure of β-Hairpin Isotopomers by FTIR, 2D IR, and Ab Initio Theory

Jianping Wang; Jianxin Chen; Robin M. Hochstrasser;