publication . Article . 2014

Apolipoprotein Gene Polymorphisms (APOB, APOC111, APOE) in the Development of Coronary Heart Disease in Ethnic Groups of Kazakhstan

Berkinbayev, S; Rysuly, M; Mussayev, A; Blum, K; Baitasova, N; Mussagaliyeva, A; Dzhunusbekova, G; Makhatov, B; Mussayev, AA; Yeshmanova, A; ...
Open Access English
  • Published: 01 Jan 2014 Journal: Journal of genetic syndrome & gene therapy, volume 5, issue 2, page 216 (eissn: 2157-7412, Copyright policy)
Background Previous Analysis of polymorphism of genes associated with the development of coronary heart disease (CHD) reveals that the frequency distribution of genotypes and alleles depends on the ethnic characteristics of the populations under study. Further impetus is derived from the well -established links between alcoholism (high prevalence in Kazakhstan region) and cardiovascular disorders. Objectives The purpose of this study was to examine a number of apolipoprotein gene polymorphisms and correlate these alleles with changes of lipid profile in CHD patients of Kazakh and Uyghur nationalities. Methods Four-Hundred Forty Eight (448) males of Kazakh and Uy...
Medical Subject Headings: lipids (amino acids, peptides, and proteins)
free text keywords: Article, Molecular Genetics, Hypertriglyceridemia, Coronary Heart Disease (CHD; Apolipoprotein Gene Polymorphisms (APOB, APOC111, APOE), Kazakhs or Uyghurs
Related Organizations
Funded by
  • Funder: National Institutes of Health (NIH)
  • Project Code: 5R37AA007112-10
NIH| Affective and Conative Changes in Alcoholism
  • Funder: National Institutes of Health (NIH)
  • Project Code: 5K05AA000219-14
Download from
47 references, page 1 of 4

Stoliarov, AV, Borokhov, AD, Zhamanbaev, EK, Bedil'baeva, GA. Alcohol as a provoking factor of suicidal behavior. ZhNevropatolPsikhiatrIm S SKorsakova. 1990; 90: 55-58

Knowles, JW1, Maeda, N. Genetic modifiers of atherosclerosis in mice. ArteriosclerThrombVascBiol. 2000; 20: 2336-2345

Cambien, F. Coronary heart disease and polymorphisms in genes affecting lipid metabolism and inflammation. CurrAtheroscler Rep. 2005; 7: 188-195

Sotos-Prieto, M1, Peñalvo, JL. Genetic variation of apolipoproteins, diet and other environmental interactions; an updated review. NutrHosp. 2013; 28: 999-1009

Goldberg, AC, Hopkins, PN, Toth, PP, Ballantyne, CM, Rader, DJ. Familial hypercholesterolemia: screening, diagnosis and management of pediatric and adult patients: clinical guidance from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. J ClinLipidol. 2011; 5: 133-140

Liu, L, Wang, M, Yang, X, Bi, M, Na, L. Fasting serum lipid and dehydroepiandrosterone sulfate as important metabolites for detecting isolated postchallenge diabetes: serum metabolomics via ultra-high-performance LC-MS. ClinChem. 2013; 59: 1338-1348

Lahiri, DK, Bye, S, Nurnberger, JI, Hodes, ME, Crisp, M. A non-organic and non-enzymatic extraction method gives higher yields of genomic DNA from whole-blood samples than do nine other methods tested. J BiochemBiophys Methods. 1992; 25: 193-205

Saiki, RK1, Gelfand, DH, Stoffel, S, Scharf, SJ, Higuchi, R. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science. 1988; 239: 487-491 [OpenAIRE] [PubMed]

Appel, E1, Eisenberg, S, Roitelman, J. Improved PCR amplification/Hhal restriction for unambiguous determination of apolipoprotein E alleles. ClinChem. 1995; 41: 187-190 [OpenAIRE]

Blackhart, BD, Ludwig, EM, Pierotti, VR, Caiati, L, Onasch, MA. Structure of the human apolipoprotein B gene. J BiolChem. 1986; 261: 15364-15367

Kim, JQ1, Song, J, Park, YB, Hong, SH. Molecular bases of coronary heart disease in Koreans. J Korean Med Sci. 1998; 13: 1-15 [OpenAIRE] [PubMed]

Kaufman, L1, Vargas, AF, Coimbra Júnior, CE, Santos, RV, Salzano, FM. Apolipoprotein B genetic variability in Brazilian Indians. Hum Biol. 1999; 71: 87-98 [OpenAIRE] [PubMed]

Hegele, RA, Huang, LS, Herbert, PN, Blum, CB, Buring, JE. Apolipoprotein B-gene DNA polymorphisms associated with myocardial infarction. N Engl J Med. 1986; 315: 1509-1515 [OpenAIRE] [PubMed]

Stepanov, VA, Puzyrev, VP, Lemza, SV, Karpov, RS, FedorovAIu, null. Interrelationship between structural variants of the apolipoprotein B and ischemic heart disease and plasma lipid levels. Genetika. 1995; 31: 405-409 [OpenAIRE] [PubMed]

Kravchenko, N, Maksimova, N. Polymorphism of the Apo B-100 Gene and Clinical Phenotypes. Achievements and Prospects of Therapy on the Eve of the Twenty-First Century. 2000: 201-208

47 references, page 1 of 4
Powered by OpenAIRE Open Research Graph
Any information missing or wrong?Report an Issue