Telomerase-dependent and independent chromosome healing in mouse embryonic stem cells

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Gao, Qing; Reynolds, Gloria E.; Wilcox, Andrew; Miller, Douglas; Cheung, Peggie; Artandi, Steven E.; Murnane, John P.;

Telomeres play an important role in protecting the ends of chromosomes and preventing chromosome fusion. We have previously demonstrated that double-strand breaks near telomeres in mammalian cells result in either the addition of a new telomere at the site of the break,... View more
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