Involvement of Rictor/mTORC2 in cardiomyocyte differentiation of mouse embryonic stem cells in vitro

Article English OPEN
Zheng, Bei; Wang, Jiadan; Tang, Leilei; Tan, Chao; Zhao, Zhe; Xiao, Yi; Ge, Renshan; Zhu, Danyan;
  • Publisher: Ivyspring International Publisher
  • Journal: International Journal of Biological Sciences,volume 13,issue 1,pages110-121 (eissn: 1449-2288)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.7150/ijbs.16312, pmc: PMC5264266
  • Subject: cardiomyocyte differentiation | Rictor/mTORC2 | embryonic stem cell | cell-cell junction | electrophysiology. | Research Paper
    mesheuropmc: digestive, oral, and skin physiology

Rictor is a key regulatory/structural subunit of the mammalian target of rapamycin complex 2 (mTORC2) and is required for phosphorylation of Akt at serine 473. It plays an important role in cell survival, actin cytoskeleton organization and other processes in embryogene... View more
Share - Bookmark