publication . Article . 2014

CA1 cell activity sequences emerge after reorganization of network correlation structure during associative learning

Modi, Mehrab N; Dhawale, Ashesh K; Bhalla, Upinder S;
Open Access English
  • Published: 01 Mar 2014 Journal: eLife, volume 3 (eissn: 2050-084X, Copyright policy)
  • Publisher: eLife Sciences Publications, Ltd
Abstract
eLife digest Ivan Pavlov famously discovered that dogs would salivate upon hearing a bell that had previously been used to signal food, even when there was no food present. This ability to connect events that occur close together in time is known as associative learning. But how is it supported within the brain? In the late 1940s, neuroscientist Donald Hebb proposed that if one neuron persistently and repeatedly takes part in firing a second neuron, the connection between the two neurons will be strengthened. Thus, if neurons that encode the sound of a bell are active at the same time as neurons that encode receiving food, connections between the two groups will...
Subjects
free text keywords: mouse, CA1, Research Article, trace conditioning, hippocampus, learning and memory, Neuroscience, activity sequences, noise correlations
51 references, page 1 of 4

Arthur D Vassilvitskii S 2007 k-means++: the advantages of careful seeding. Proceedings of the Eighteenth Annual ACM-SIAM Symposium on Discrete Algorithms[Internet] p. 1027–1035 Available from: http://dl.acm.org/citation.cfm?id=1283383.1283494

Baeg EH Kim YB Huh K Mook-Jung I Kim HT Jung MW 2003 Dynamics of population code for working memory in the prefrontal cortex. Neuron 40:177–188. 10.1016/S0896-6273(03)00597-X 14527442 [OpenAIRE] [PubMed] [DOI]

Bair W Zohary E Newsome WT 2001 Correlated firing in macaque visual area MT: time scales and relationship to behavior. Journal of Neuroscience 21:1676–1697 11222658 [OpenAIRE] [PubMed]

Bliss TVP Collingridge GL 1993 A synaptic model of memory: long term potentiation in the hippocampus. Nature 361:31–39. 10.1038/361031a0 8421494 [PubMed] [DOI]

Brivanlou IH Dantzker JLM Stevens CF Callaway EM 2004 Topographic specificity of functional connections from hippocampal CA3 to CA1. Proceedings of the National Academy of Sciences of the United States of America 101:2560–2565. 10.1073/pnas.0308577100 14983048 [OpenAIRE] [PubMed] [DOI]

Büchel C Dolan RJ Armony JL Friston KJ 1999 Amygdala–hippocampal involvement in human aversive trace conditioning revealed through event-related functional magnetic resonance imaging. Journal of Neuroscience 19:10869–10876 10594068 [OpenAIRE] [PubMed]

Cheng S Frank LM 2008 New experiences enhance coordinated neural activity in the hippocampus. Neuron 57:303–313. 10.1016/j.neuron.2007.11.035 18215626 [OpenAIRE] [PubMed] [DOI]

CzurkóHHA Csicsvari J Buzsáki G 1999 Firing rate and theta-phase coding by hippocampal pyramidal neurons during “space clamping”. European Journal of Neuroscience 11:4373–4380. 10.1046/j.1460-9568.1999.00853.x 10594664 [PubMed] [DOI]

Dombeck DA Graziano MS Tank DW 2009 Functional clustering of neurons in motor cortex determined by cellular resolution imaging in awake behaving mice. Journal of Neuroscience 29:13751–13760. 10.1523/JNEUROSCI.2985-09.2009 19889987 [OpenAIRE] [PubMed] [DOI]

Dombeck DA Harvey CD Tian L Looger LL Tank DW 2010 Functional imaging of hippocampal place cells at cellular resolution during virtual navigation. Nature Neuroscience 13:1433–1440. 10.1038/nn.2648 [OpenAIRE] [DOI]

Dombeck DA Khabbaz AN Collman F Adelman TL Tank DW 2007 Imaging large-scale neural activity with cellular resolution in awake, mobile mice. Neuron 56:43–57. 10.1016/j.neuron.2007.08.003 17920014 [OpenAIRE] [PubMed] [DOI]

Dragoi G Tonegawa S 2011 Preplay of future place cell sequences by hippocampal cellular assemblies. Nature 469:397–401. 10.1038/nature09633 21179088 [OpenAIRE] [PubMed] [DOI]

Dragoi G Tonegawa S 2013 Development of schemas revealed by prior experience and NMDA receptor knock-out. eLife 2:e01326. 10.7554/eLife.01326 24327561 [OpenAIRE] [PubMed] [DOI]

Egorov AV Hamam BN Fransén E Hasselmo ME Alonso AA 2002 Graded persistent activity in entorhinal cortex neurons. Nature 420:173–178. 10.1038/nature01171 12432392 [PubMed] [DOI]

Fenton AA Muller RU 1998 Place cell discharge is extremely variable during individual passes of the rat through the firing field. Proceedings of the National Academy of Sciences of the United States of America 95:3182–3187. 10.1073/pnas.95.6.3182 9501237 [OpenAIRE] [PubMed] [DOI]

51 references, page 1 of 4
Abstract
eLife digest Ivan Pavlov famously discovered that dogs would salivate upon hearing a bell that had previously been used to signal food, even when there was no food present. This ability to connect events that occur close together in time is known as associative learning. But how is it supported within the brain? In the late 1940s, neuroscientist Donald Hebb proposed that if one neuron persistently and repeatedly takes part in firing a second neuron, the connection between the two neurons will be strengthened. Thus, if neurons that encode the sound of a bell are active at the same time as neurons that encode receiving food, connections between the two groups will...
Subjects
free text keywords: mouse, CA1, Research Article, trace conditioning, hippocampus, learning and memory, Neuroscience, activity sequences, noise correlations
51 references, page 1 of 4

Arthur D Vassilvitskii S 2007 k-means++: the advantages of careful seeding. Proceedings of the Eighteenth Annual ACM-SIAM Symposium on Discrete Algorithms[Internet] p. 1027–1035 Available from: http://dl.acm.org/citation.cfm?id=1283383.1283494

Baeg EH Kim YB Huh K Mook-Jung I Kim HT Jung MW 2003 Dynamics of population code for working memory in the prefrontal cortex. Neuron 40:177–188. 10.1016/S0896-6273(03)00597-X 14527442 [OpenAIRE] [PubMed] [DOI]

Bair W Zohary E Newsome WT 2001 Correlated firing in macaque visual area MT: time scales and relationship to behavior. Journal of Neuroscience 21:1676–1697 11222658 [OpenAIRE] [PubMed]

Bliss TVP Collingridge GL 1993 A synaptic model of memory: long term potentiation in the hippocampus. Nature 361:31–39. 10.1038/361031a0 8421494 [PubMed] [DOI]

Brivanlou IH Dantzker JLM Stevens CF Callaway EM 2004 Topographic specificity of functional connections from hippocampal CA3 to CA1. Proceedings of the National Academy of Sciences of the United States of America 101:2560–2565. 10.1073/pnas.0308577100 14983048 [OpenAIRE] [PubMed] [DOI]

Büchel C Dolan RJ Armony JL Friston KJ 1999 Amygdala–hippocampal involvement in human aversive trace conditioning revealed through event-related functional magnetic resonance imaging. Journal of Neuroscience 19:10869–10876 10594068 [OpenAIRE] [PubMed]

Cheng S Frank LM 2008 New experiences enhance coordinated neural activity in the hippocampus. Neuron 57:303–313. 10.1016/j.neuron.2007.11.035 18215626 [OpenAIRE] [PubMed] [DOI]

CzurkóHHA Csicsvari J Buzsáki G 1999 Firing rate and theta-phase coding by hippocampal pyramidal neurons during “space clamping”. European Journal of Neuroscience 11:4373–4380. 10.1046/j.1460-9568.1999.00853.x 10594664 [PubMed] [DOI]

Dombeck DA Graziano MS Tank DW 2009 Functional clustering of neurons in motor cortex determined by cellular resolution imaging in awake behaving mice. Journal of Neuroscience 29:13751–13760. 10.1523/JNEUROSCI.2985-09.2009 19889987 [OpenAIRE] [PubMed] [DOI]

Dombeck DA Harvey CD Tian L Looger LL Tank DW 2010 Functional imaging of hippocampal place cells at cellular resolution during virtual navigation. Nature Neuroscience 13:1433–1440. 10.1038/nn.2648 [OpenAIRE] [DOI]

Dombeck DA Khabbaz AN Collman F Adelman TL Tank DW 2007 Imaging large-scale neural activity with cellular resolution in awake, mobile mice. Neuron 56:43–57. 10.1016/j.neuron.2007.08.003 17920014 [OpenAIRE] [PubMed] [DOI]

Dragoi G Tonegawa S 2011 Preplay of future place cell sequences by hippocampal cellular assemblies. Nature 469:397–401. 10.1038/nature09633 21179088 [OpenAIRE] [PubMed] [DOI]

Dragoi G Tonegawa S 2013 Development of schemas revealed by prior experience and NMDA receptor knock-out. eLife 2:e01326. 10.7554/eLife.01326 24327561 [OpenAIRE] [PubMed] [DOI]

Egorov AV Hamam BN Fransén E Hasselmo ME Alonso AA 2002 Graded persistent activity in entorhinal cortex neurons. Nature 420:173–178. 10.1038/nature01171 12432392 [PubMed] [DOI]

Fenton AA Muller RU 1998 Place cell discharge is extremely variable during individual passes of the rat through the firing field. Proceedings of the National Academy of Sciences of the United States of America 95:3182–3187. 10.1073/pnas.95.6.3182 9501237 [OpenAIRE] [PubMed] [DOI]

51 references, page 1 of 4
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