Heterogeneity of mprF Sequences in Methicillin-Resistant Staphylococcus aureus Clinical Isolates: Role in Cross-Resistance between Daptomycin and Host Defense Antimicrobial Peptides

Other literature type English OPEN
Bayer, Arnold S.; Mishra, Nagendra N.; Sakoulas, George; Nonejuie, Poochit; Nast, Cynthia C.; Pogliano, Joseph; Chen, Kuan-Tsen; Ellison, Steven N.; Yeaman, Michael R.; Yang, Soo-Jin;
(2014)

Over the past several years, single-nucleotide polymorphisms (SNPs) within the mprF open reading frame (ORF) have been proposed to be associated with a gain-of-function phenotype in terms of daptomycin (DAP) nonsusceptibility (referred to as daptomycin resistance [DAP-R... View more
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