Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model

Other literature type English OPEN
Bordeleau, Marie-Eve; Robert, Francis; Gerard, Baudouin; Lindqvist, Lisa; Chen, Samuel M.H.; Wendel, Hans-Guido; Brem, Brigitte; Greger, Harald; Lowe, Scott W.; Porco, John A.; Pelletier, Jerry;
(2008)

Disablement of cell death programs in cancer cells contributes to drug resistance and in some cases has been associated with altered translational control. As eukaryotic translation initiation factor 4E (eIF4E) cooperates with c-Myc during lymphomagenesis, induces drug ... View more
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