Pharmacodynamic effects of daclizumab in the intrathecal compartment

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Komori, Mika; Kosa, Peter; Stein, Jason; Zhao, Vivian; Blake, Andrew; Cherup, Jamie; Sheridan, James; Wu, Tianxia; Bielekova, Bibiana;

Abstract Objective It was previously demonstrated that daclizumab therapy normalizes cellular cerebrospinal fluid (CSF) abnormalities typical of multiple sclerosis (MS) in the majority of treated patients. However, CSF cells represent only the mobile portion of intrathe... View more
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