Interaction with CagF Is Required for Translocation of CagA into the Host via the Helicobacter pylori Type IV Secretion System

Other literature type English OPEN
Couturier, Marc Roger; Tasca, Elizabetta; Montecucco, Cesare; Stein, Markus;
  • Publisher: American Society for Microbiology
  • Related identifiers: doi: 10.1128/IAI.74.1.273-281.2006, pmc: PMC1346642
  • Subject: Molecular Pathogenesis
    mesheuropmc: digestive system | bacteria | bacterial infections and mycoses | digestive system diseases

Development of severe gastric diseases is strongly associated with those strains of Helicobacter pylori that contain the cag pathogenicity island (PAI) inserted into the chromosome. The cag PAI encodes a type IV secretion system that translocates the major disease-assoc... View more
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