publication . Article . 2012

P01.07. The Chinese herbs Chuan Bei Mu and Huang Qin can produce dose-dependent biphasic response in endometrial cancer cells

Ahmad, K; Pirog, J; Syed, V; Jiang, Y; Nguyen, H;
Open Access
  • Published: 01 Jun 2012 Journal: BMC Complementary and Alternative Medicine, volume 12, page P7 (issn: 1472-6882, Copyright policy)
  • Publisher: Springer Nature
Abstract
Results We found that at low doses Huang Qin induced cytotoxicity (1 μg/ml), but at high doses, 50-300 μg/ml, the same herb induced cell proliferation. Chuan Bei Mu exhibited a similar biphasic response with cytoxicity at 1-200 μg/ml but proliferation at 400 μg/ml. Data on Lian Qiao was scattered but the herb induced cytotoxicity at low doses from 1-10 μg/ml and less significantly at high doses. Bai Zhi was the only herb that did not induce cytotoxicity in endometrial cancer cells.
Subjects
Medical Subject Headings: complex mixtures
free text keywords: Complementary and alternative medicine, General Medicine, Cancer cell, Cell growth, Herb, food.ingredient, food, Endometrial cancer, medicine.disease, medicine, business.industry, business, Cytotoxicity, Traditional medicine, Bioactive compound, chemistry.chemical_compound, chemistry, Chinese herbs, Poster Presentation, Other systems of medicine, RZ201-999
Funded by
NIH| International Research Conference on Integrative Medicine
Project
  • Funder: National Institutes of Health (NIH)
  • Project Code: 3R13AT007128-01S1
  • Funding stream: NATIONAL CENTER FOR COMPLEMENTARY & ALTERNATIVE MEDICINE
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