Mukaiyama Aldol Reactions in Aqueous Media

Article English OPEN
Kitanosono, Taku; Kobayashi, Shū;
  • Publisher: WILEY-VCH Verlag
  • Journal: Advanced Synthesis & Catalysis,volume 355,issue 16,pages3,095-3,118 (issn: 1615-4150, eissn: 1615-4169)
  • Related identifiers: pmc: PMC4065357, doi: 10.1002/adsc.201300798
  • Subject: aldol reaction | Lewis acids | Review | asymmetric catalysis | green chemistry | water
    mesheuropmc: polycyclic compounds | organic chemicals

Mukaiyama aldol reactions in aqueous media have been surveyed. While the original Mukaiyama aldol reactions entailed stoichiometric use of Lewis acids in organic solvents under strictly anhydrous conditions, Mukaiyama aldol reactions in aqueous media are not only suitab... View more
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