Dysregulation of interleukin 4, interleukin 5, and interferon gamma gene expression in steroid-resistant asthma

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In steroid-resistant (SR) asthma, there is a lack of clinical responsiveness to oral prednisone. Previous studies indicate that this may be explained by the effect of the combination of interleukin 2 (IL- 2) and IL-4 on glucocorticoid receptor binding affinity. By contr... View more
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