TOMM40 poly-T variants and Cerebrospinal Fluid Amyloid Beta levels in the elderly

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Pomara, Nunzio; Bruno, Davide; Nierenberg, Jay J.; Sidtis, John J.; Martiniuk, Frank T.; Mehta, Pankaj D.; Zetterberg, Henrik; Blennow, Kaj;

A variable poly-T polymorphism in the TOMM40 gene, which is in linkage disequilibrium with APOE, was recently implicated with increased risk and earlier onset age for late-onset Alzheimer’s disease in APOE ε3 carriers. To elucidate potential neurobiological mechanisms u... View more
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