publication . Other literature type . Article . 2012

Applications of p-hydroxyphenacyl (pHP) and coumarin-4-ylmethyl photoremovable protecting groups

Richard S. Givens; Marina Rubina; Jakob Wirz;
  • Published: 16 Feb 2012
Abstract
Most applications of photoremovable protecting groups have used o-nitrobenzyl compounds and their (often commercially available) derivatives that, however, have several disadvantages. The focus of this review is on applications of the more recently developed title compounds, which are especially well suited for time-resolved biochemical and physiological investigations, because they release the caged substrates in high yield within a few nanoseconds or less. Together, these two chromophores cover the action spectrum for photorelease from >700 nm to 250 nm.
Subjects
free text keywords: Article, Physical and Theoretical Chemistry, Coumarin, chemistry.chemical_compound, chemistry, Molecule, Chromophore, Phenylacetates, Photodissociation, Photochemistry
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publication . Other literature type . Article . 2012

Applications of p-hydroxyphenacyl (pHP) and coumarin-4-ylmethyl photoremovable protecting groups

Richard S. Givens; Marina Rubina; Jakob Wirz;