Insertions and deletions trigger adaptive walks in Drosophila proteins

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Leushkin, Evgeny V.; Bazykin, Georgii A.; Kondrashov, Alexey S.;
(2012)

Maps that relate all possible genotypes or phenotypes to fitness—fitness landscapes—are central to the evolution of life, but remain poorly known. An insertion or a deletion (indel) of one or several amino acids constitutes a substantial leap of a protein within the spa... View more
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