Differential Membrane Binding Mechanics of Synaptotagmin Isoforms Observed at Atomic Detail

Other literature type English OPEN
Vermaas, Josh V.; Tajkhorshid, Emad;
(2016)

Synaptotagmin (Syt) is a membrane-associated protein involved in vesicle fusion through the SNARE complex that is found throughout the human body in 17 different isoforms. These isoforms have two membrane-binding C2 domains, which sense Ca2+ and thereby promote anionic ... View more
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