TXNIP mediates the differential responses of A549 cells to sodium butyrate and sodium 4‐phenylbutyrate treatment

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Jin, Xuefang ; Wu, Nana ; Dai, Juji ; Li, Qiuxia ; Xiao, XiaoQiang (2016)
  • Publisher: John Wiley and Sons Inc.
  • Journal: Cancer Medicine, volume 6, issue 2, pages 424-438 (eissn: 2045-7634)
  • Related identifiers: pmc: PMC5313639, doi: 10.1002/cam4.977
  • Subject: mitochondrial superoxide | butyrate | histone modification | A549 cells | Original Research | Cancer Biology | TXNIP

Abstract Sodium butyrate (NaBu) and sodium 4‐phenylbutyrate (4PBA) have promising futures in cancer treatment; however, their underlying molecular mechanisms are not clearly understood. Here, we show A549 cell death induced by NaBu and 4PBA are not the same. NaBu treatm... View more
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