Increased Substitution Rates Surrounding Low-Complexity Regions within Primate Proteins

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Lenz, Carolyn; Haerty, Wilfried; Golding, G. Brian;
(2014)
  • Publisher: Oxford University Press
  • Journal: Genome Biology and Evolution,volume 6,issue 3,pages655-665 (eissn: 1759-6653)
  • Related identifiers: doi: 10.1093/gbe/evu042, pmc: PMC3971593
  • Subject: primate | mutation | Research Article | substitution | low-complexity region

Previous studies have found that DNA-flanking low-complexity regions (LCRs) have an increased substitution rate. Here, the substitution rate was confirmed to increase in the vicinity of LCRs in several primate species, including humans. This effect was also found among ... View more
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