publication . Article . 2017

Multi-antibiotic resistant extended-spectrum beta-lactamase producing bacteria pose a challenge to the effective treatment of wound and skin infections

Oli, Angus Nnamdi; Eze, Dennis Emeka; Gugu, Thaddeus Harrison; Ezeobi, Ifeanyi; Maduagwu, Ukamaka Nwakaku; Ihekwereme, Chibueze Peter;
Open Access English
  • Published: 01 May 2017 Journal: The Pan African Medical Journal, volume 27 (eissn: 1937-8688, Copyright policy)
  • Publisher: The African Field Epidemiology Network
Abstract
Introduction The increasing incidence of antibiotic resistant bacteria is a concern both to the clinicians and the patients due to obvious consequences such as treatment failures, prolonged patients’ stay in hospital and nosocomial infections. The choice of the first antibiotic therapy in emergency wards in hospitals is usually not based on patient-specific microbial culture and susceptibility test result.This study is aimed at profiling extended-spectrum beta-lactamase (ESBL) producing bacteria associated with wound injuries and highlighting their multi-antibiotic resistance character. Methods Sixty-three wound swab samples were collected and cultured on nutrie...
Subjects
free text keywords: bacteria isolates, E. coli, multi-antibiotic resistance, SBL, wound/skin infections, Research
Related Organizations
39 references, page 1 of 3

Aibinu, IE, Ohagbulam, VC, Adenipekun, EA, Ogunsola, FT, Odugbemi, TO, Mee, BJ. Extended-spectrum beta-lactamase enzymes in clinical isolates of Enterobacter species from Lagos, Nigeria. J ClinMicrobiol. 2003; 41 (5): 2197-2200 [OpenAIRE]

Bharat Pokharel, M, Janak, Koirala, Rajan Dahal, K, Shyam Mishra, K, Prem Khadga, K, Tuladhar, NR. Multidrug-resistant and extended-spectrum beta-lactamase (ESBL)-producing Salmonella enterica (serotypes Typhi and Paratyphi A) from blood isolates in Nepal: surveillance of resistance and a search for newer alternatives. International Journal of Infectious Diseases. 2006; 10: 434-438 [OpenAIRE] [PubMed]

Maina, Daniel, Makau, Paul, Nyerere, Andrew, Revathi, Gunturu. Antimicrobial resistance patterns in extended-spectrum β-lactamase producing Escherichia coli and Klebsiella pneumoniae isolates in a private tertiary hospital, Kenya. Microbiology Discovery. 2013; 1 (5): 1-4

Fang, Hong, Ataker, Ferda, Hedin, Go¨ran, Dornbusch, Kathrine. Molecular epidemiology of extended-spectrum β-lactamases among Escherichia coli isolates collected in a Swedish hospital and its associated health care facilities from 2001 to 2006. J Clin Microbiol. 2008; 46 (2): 707-712 [OpenAIRE] [PubMed]

Oluduro Anthonia, Olufunke, Aregbesola Oladipupo, Abiodun, Fashina Christina, Dunah. 2014 Extended Spectrum Beta- Lactamase- Producing Uropathogenic Escherichia coli in Pregnant Women Diagnosed With Urinary Tract Infections in South-Western Nigeria. Journal of Molecular Biology Research. 2014; 4 (1): 34-41

Paterson, DL, Bonomo, RA. Extended-spectrum β-lactamases: a clinical update. Clin Microbiol Rev. 2005; 18 (4): 657-86 [OpenAIRE] [PubMed]

Ramphal, R, Ambrose, PG. Extended-spectrum beta-lactamases and clinical outcomes: current data. Clin Infect Dis. 2006; 42 (Suppl 4): S164-72 [PubMed]

Pitout Johann, DD, Nordmann, Patrice, Laupland Kevin, B, Poirel, Laurent. Emergence of Enterobacteriaceae producing extended-spectrum β-lactamases (ESBLs) in the community. J Antimicrob Chemother. 2005; 56: 52-59 [PubMed]

Arzai, AH, Adamu, DJM. Prevalence of beta-lactamase Producers among randomly selected bacterial pathogens in Kano, Nigeria. Biological and Environmental Sciences Journal for the Tropics. 2008; 5 (3): 218-223

Yusuf, I, Haruna, M, Yahaya, H. Prevalence and antibiotic susceptibility of ampc and ESBL producing clinical isolates at a tertiary health care center in Kano, northwest Nigeria. African Journal of Clinical and Experimental Microbiology. 2013; 14 (2): 109-119 [OpenAIRE]

Iroha, IR, Adikwu, MU, Esimone, CO, Aibinu, I, Amadi, ES. Extended spectrum Beta-Lactamase (EBSL) in E coli isolated from a tertiary hospital in Enugu state, Nigeria. Pak J Med Sci. 2009; 25 (2): 279-282

Afunwa, RA, Odimegwu, DC, Iroha, RI, Esimone, CO. Antimicrobial resistance status and prevalence rates of extended spectrum beta-lactamase (ESBL) producers isolated from a mixed human population. Bosn J Basic Med Sci. 2011; 11 (2): 91-6 [OpenAIRE] [PubMed]

Song, W, Lee, KM, Kang, HJ, Shin, DH, Kim, DK. Microbiologic aspects of predominant bacteria isolated from the burn patients in Korea. Burns. 2001; 27 (2): 136-9 [PubMed]

Oli Angus, Nnamdi, Ekejindu Callistus, Chibuike, Ejiofor Obiora, Shedrack, Oli Adaobi, Helen, Ezeobi, Ifeanyi, Ibeh Christian, Chibuzo. The knowledge of and attitude to hospital-acquired infections among public and private healthcare workers in South-East, Nigeria. British Journal of Medicine & Medical Research. 2016; 11 (3): 1-10

Blomberg, B, Jureen, R, Manji, KP, Tamim, BS, Mwakagile, DS, Urassa, WK, Fataki, M, Msangi, V, Tellevik, MG, Maselle, SY, Langeland, N. High rate of fatal pediatric septicemia caused by gram-negative bacteria with extended-spectrum beta lactamases in Dares Salaam, Tanzania. Journal of Clinical Microbiology. 2005; 43: 745-49 [OpenAIRE] [PubMed]

39 references, page 1 of 3
Abstract
Introduction The increasing incidence of antibiotic resistant bacteria is a concern both to the clinicians and the patients due to obvious consequences such as treatment failures, prolonged patients’ stay in hospital and nosocomial infections. The choice of the first antibiotic therapy in emergency wards in hospitals is usually not based on patient-specific microbial culture and susceptibility test result.This study is aimed at profiling extended-spectrum beta-lactamase (ESBL) producing bacteria associated with wound injuries and highlighting their multi-antibiotic resistance character. Methods Sixty-three wound swab samples were collected and cultured on nutrie...
Subjects
free text keywords: bacteria isolates, E. coli, multi-antibiotic resistance, SBL, wound/skin infections, Research
Related Organizations
39 references, page 1 of 3

Aibinu, IE, Ohagbulam, VC, Adenipekun, EA, Ogunsola, FT, Odugbemi, TO, Mee, BJ. Extended-spectrum beta-lactamase enzymes in clinical isolates of Enterobacter species from Lagos, Nigeria. J ClinMicrobiol. 2003; 41 (5): 2197-2200 [OpenAIRE]

Bharat Pokharel, M, Janak, Koirala, Rajan Dahal, K, Shyam Mishra, K, Prem Khadga, K, Tuladhar, NR. Multidrug-resistant and extended-spectrum beta-lactamase (ESBL)-producing Salmonella enterica (serotypes Typhi and Paratyphi A) from blood isolates in Nepal: surveillance of resistance and a search for newer alternatives. International Journal of Infectious Diseases. 2006; 10: 434-438 [OpenAIRE] [PubMed]

Maina, Daniel, Makau, Paul, Nyerere, Andrew, Revathi, Gunturu. Antimicrobial resistance patterns in extended-spectrum β-lactamase producing Escherichia coli and Klebsiella pneumoniae isolates in a private tertiary hospital, Kenya. Microbiology Discovery. 2013; 1 (5): 1-4

Fang, Hong, Ataker, Ferda, Hedin, Go¨ran, Dornbusch, Kathrine. Molecular epidemiology of extended-spectrum β-lactamases among Escherichia coli isolates collected in a Swedish hospital and its associated health care facilities from 2001 to 2006. J Clin Microbiol. 2008; 46 (2): 707-712 [OpenAIRE] [PubMed]

Oluduro Anthonia, Olufunke, Aregbesola Oladipupo, Abiodun, Fashina Christina, Dunah. 2014 Extended Spectrum Beta- Lactamase- Producing Uropathogenic Escherichia coli in Pregnant Women Diagnosed With Urinary Tract Infections in South-Western Nigeria. Journal of Molecular Biology Research. 2014; 4 (1): 34-41

Paterson, DL, Bonomo, RA. Extended-spectrum β-lactamases: a clinical update. Clin Microbiol Rev. 2005; 18 (4): 657-86 [OpenAIRE] [PubMed]

Ramphal, R, Ambrose, PG. Extended-spectrum beta-lactamases and clinical outcomes: current data. Clin Infect Dis. 2006; 42 (Suppl 4): S164-72 [PubMed]

Pitout Johann, DD, Nordmann, Patrice, Laupland Kevin, B, Poirel, Laurent. Emergence of Enterobacteriaceae producing extended-spectrum β-lactamases (ESBLs) in the community. J Antimicrob Chemother. 2005; 56: 52-59 [PubMed]

Arzai, AH, Adamu, DJM. Prevalence of beta-lactamase Producers among randomly selected bacterial pathogens in Kano, Nigeria. Biological and Environmental Sciences Journal for the Tropics. 2008; 5 (3): 218-223

Yusuf, I, Haruna, M, Yahaya, H. Prevalence and antibiotic susceptibility of ampc and ESBL producing clinical isolates at a tertiary health care center in Kano, northwest Nigeria. African Journal of Clinical and Experimental Microbiology. 2013; 14 (2): 109-119 [OpenAIRE]

Iroha, IR, Adikwu, MU, Esimone, CO, Aibinu, I, Amadi, ES. Extended spectrum Beta-Lactamase (EBSL) in E coli isolated from a tertiary hospital in Enugu state, Nigeria. Pak J Med Sci. 2009; 25 (2): 279-282

Afunwa, RA, Odimegwu, DC, Iroha, RI, Esimone, CO. Antimicrobial resistance status and prevalence rates of extended spectrum beta-lactamase (ESBL) producers isolated from a mixed human population. Bosn J Basic Med Sci. 2011; 11 (2): 91-6 [OpenAIRE] [PubMed]

Song, W, Lee, KM, Kang, HJ, Shin, DH, Kim, DK. Microbiologic aspects of predominant bacteria isolated from the burn patients in Korea. Burns. 2001; 27 (2): 136-9 [PubMed]

Oli Angus, Nnamdi, Ekejindu Callistus, Chibuike, Ejiofor Obiora, Shedrack, Oli Adaobi, Helen, Ezeobi, Ifeanyi, Ibeh Christian, Chibuzo. The knowledge of and attitude to hospital-acquired infections among public and private healthcare workers in South-East, Nigeria. British Journal of Medicine & Medical Research. 2016; 11 (3): 1-10

Blomberg, B, Jureen, R, Manji, KP, Tamim, BS, Mwakagile, DS, Urassa, WK, Fataki, M, Msangi, V, Tellevik, MG, Maselle, SY, Langeland, N. High rate of fatal pediatric septicemia caused by gram-negative bacteria with extended-spectrum beta lactamases in Dares Salaam, Tanzania. Journal of Clinical Microbiology. 2005; 43: 745-49 [OpenAIRE] [PubMed]

39 references, page 1 of 3
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