Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia
Other literature type
Salomon, Benoît L.
Cohen, José L.
- Publisher: American Society for Clinical Investigation
mesheuropmc: surgical procedures, operative | chemical and pharmacologic phenomena
CD4+CD25+ regulatory T cells (Treg’s) play a pivotal role in preventing organ-specific autoimmune diseases and in inducing tolerance to allogeneic organ transplants. We and others recently demonstrated that high numbers of Treg’s can also modulate graft-versus-host dise...